LCMT1 |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Protein_LCMT1_PDB_3IEI.png/250px-Protein_LCMT1_PDB_3IEI.png) |
Available structures |
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PDB | Human UniProt search: PDBe RCSB |
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List of PDB id codes |
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3IEI, 3O7W, 3P71 |
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Identifiers |
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Aliases | LCMT1, LCMT, PPMT1, CGI-68, leucine carboxyl methyltransferase 1 |
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External IDs | OMIM: 610286; MGI: 1353593; HomoloGene: 41123; GeneCards: LCMT1; OMA:LCMT1 - orthologs |
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Gene location (Human) |
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![Chromosome 16 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2d/Ideogram_human_chromosome_16.svg/300px-Ideogram_human_chromosome_16.svg.png) | Chr. | Chromosome 16 (human)[1] |
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| Band | 16p12.1 | Start | 25,111,731 bp[1] |
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End | 25,178,231 bp[1] |
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Gene location (Mouse) |
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![Chromosome 7 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/e/e4/Ideogram_house_mouse_chromosome_7.svg/260px-Ideogram_house_mouse_chromosome_7.svg.png) | Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 F3 | Start | 122,969,007 bp[2] |
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End | 123,029,581 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - middle temporal gyrus
- body of pancreas
- prefrontal cortex
- oocyte
- nucleus accumbens
- right frontal lobe
- gonad
- pons
- Brodmann area 23
- anterior cingulate cortex
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| Top expressed in | - lacrimal gland
- dentate gyrus of hippocampal formation granule cell
- Region I of hippocampus proper
- ventromedial nucleus
- medial ganglionic eminence
- anterior amygdaloid area
- nucleus accumbens
- nucleus of stria terminalis
- dorsomedial hypothalamic nucleus
- superior frontal gyrus
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d0/PBB_GE_LCMT1_221515_s_at_fs.png/250px-PBB_GE_LCMT1_221515_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - methyltransferase activity
- protein methyltransferase activity
- S-adenosylmethionine-dependent methyltransferase activity
- transferase activity
- protein binding
- protein C-terminal carboxyl O-methyltransferase activity
- protein C-terminal leucine carboxyl O-methyltransferase activity
| Cellular component | | Biological process | - regulation of mitotic cell cycle spindle assembly checkpoint
- methylation
- C-terminal protein methylation
- regulation of glucose metabolic process
- regulation of apoptotic process
- negative regulation of protein-containing complex assembly
- protein methylation
- G2/M transition of mitotic cell cycle
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001032391 NM_016309 NM_016015 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 16: 25.11 – 25.18 Mb | Chr 7: 122.97 – 123.03 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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